Objective: To improve the development and utilization rate of Lycium barbarum in the saline-alkali land of the Yellow River Delta. Methods: Ultraviolet spectrophotometer was used to determine the scavenging effect of Lycium barbarum oligosaccharide on free radicals and its effect on the growth curve and pH value of Bifidobacterium adolescentis, so as to determine its antioxidant performance and the ability to proliferate probiotics. Results: The concentration of Lycium barbarum oligosaccharide reached 2.0 mg/mL, the maximum scavenging rates of DPPH·, ABTS+ and hydroxyl radical reached (65.32±0.03)%, (99.93±0.05)% and (21.86±0.01)%, respectively, when the concentration was between 0.1~0.5 mg/mL, it showed good total reducing power. The OD value of Bifidobacterium adolescentis increased with the increase of Lycium barbarum oligosaccharide concentration, and the pH value was negatively correlated with the cell concentration. Conclusion: Lycium barbarum oligosaccharides show strong antioxidant activity and the ability to proliferate probiotics.

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[1] JIN M,HUANG Q,ZHAO K,et al.Biological activities and potential health benefit effects of polysaccharides isolated from Lycium barbarum L.[J].International Journal Biological Macromolecules,2013,54:16-23.
[2] GAN L,ZHANG S H.Effect of Lycium barbarum polysaccharides on anti-tumor activity and immune function[J].Acta Nutrimenta Sinica,2003,25:200-202.
[3] CHENG J,ZHOU Z W,SHENG H P,et al.An evidence-based update on the pharmacological activities and possible molecular targets of Lycium barbarum polysaccharides[J].Drug Design Development and Therapy,2015,9:33-78.
[4] ZHOU F,JIANG X,WANG T,et al.Lycium barbarum Polysaccharide(LBP):A novel prebiotics candidate for Bifidobacterium and Lactobacillus[J].Front Microbiol,2018,9:1034.
[5] YANG Y,CHANG Y,WU Y,et al.A homogeneous polysaccharide from Lycium barbarum:Structural characterizations,anti-obesity effects and impacts on gut microbiota[J].International Journal Biological Macromolecules,2021,183:2 074-2 087.
[6] CAI H Z,LIU F K,ZUO P G,et al.Practical application of antidiabetic efficacy of Lycium barbarum polysaccharide in patients with type 2 diabetes[J].Medicinal Chemistry,2015,11:383-390.
[7] YANG Y,LI W,LI Y,et al.Dietary Lycium barbarum polysaccharide induces Nrf2/ARE pathway and ameliorates insulin resistance induced by high-fat via activation of PI3K/AKT signaling[J].Oxidative Medicine and Cell Longevity,2014,2 014:145641.
[8] ZHOU L S,LIAO W F,Chen X,et al.An arabinogalactan from fruits of Lycium barbarum L.inhibits production and aggregation of Aβ42[J].Carbohydrate Polymers,2018,195:643-651.
[9] CAO C,ZHU B W,LIU Z Q,et al.An arabinogalactan from Lycium barbarum attenuates DSS-induced chronic colitis in C57BL/6J mice associated with the modulation of intestinal barrier function and gut microbiota[J].Food & Function,2021,12(20):9 829-9 843.
[10] MOURA F A D,MACAGNAN F T,SILVA L P D,et al.Oligosaccharide production by hydrolysis of polysaccharides:A review[J].International Journal of Food Science & Technology,2015,50(2):275-281.
[11] 王辉.益生元应用研究进展[J].食品安全导刊,2016(3):87-88.WANG Hui.Research progress of prebiotic application[J].Food Safety Guide,2016(3):87-88.
[12] ZHANG X R,ZHOU W X,ZHANG Y X,et al.Macrophages,rather than T and B cells are principal immunostimulatory target cells of Lycium barbarum L.polysaccharide LBPF4-OL[J].J Ethnopharmacology,2011,136(3):465-472.
[13] JIANG L F.Preparation and antioxidant activity of Lycium barbarum oligosaccharides[J].Carbohydrate Polymers,2014,99:646-648.
[14] 许盼盼.枸杞抗盐种质资源筛选与抗盐基因的克隆鉴定[D].咸阳:西北农林科技大学,2018:12-14.XU Pan-pan.Screening of Lyciumsalt-resistant germplasm resources and identification of salt-resistant genes[D].Xianyang:Northwest A&F University,2018:12-14.
[15] WANG Y L,ZHAO C Y,MA Q L,et al.Carbon benefits of wolfberry plantation on secondary saline land in jingtai oasis,gansu-a case study on application of the CBP model[J].Journal of Environmental Management,2015,157:303-310.
[16] 贾晓东,任全进,浦东,等.耐盐碱药赏两用植物的筛选和利用[J].江苏农业科学,2010(6):287-289.JIA Xiao-dong,REN Quan-jin,PU Dong,et al.Screening and utilization of salt and alkali tolerant plants[J].Jiangsu Agricultural Sciences,2010(6):287-289.
[17] DING Y,CHEN D,YAN Y,et al.Effects of long-term consumption of polysaccharides from the fruit of Lycium barbarum on host's health[J].Food Research International,2021,139:109913.
[18] 冯永俠.枸杞多糖超声浸提浓缩与抗氧化活性研究[D].天津:天津科技大学,2020:22-28.FENG Yong-xia.Study on ultrasonic extraction and ultrasonic concentration and antioxidant activity of Lycium barbarum polysaccharide[D].Tianjin:Tianjin University of science and technology,2020:22-28.
[19] 曹叶霞,王泽慧,贺金凤,等.静乐黑枸杞多糖的提取及抗氧化性分析[J].食品工业科技,2019,40(14):196-202.CAO Ye-xia,WANG Ze-hui,HE Jin-feng,et al.Extracting polysaccharide from Lycium ruthenicum of Jingle and its antioxidant acitvity[J].Science and Technology of Food Industry,2019,40(14):196-202.
[20] SIDDHURAJU P,BECKER K.The antioxidant and free radical scavenging activities of processed cowpea(Vigna unguiculata(L.)Walp.)seed extracts[J].Food Chemistry,2007,101(1):10-19.
[21] 孙玉姣,侯淑婷,鱼喆喆,等.宁夏红果枸杞多糖提取及其体外抗氧化活性研究[J].陕西科技大学学报,2018,36(5):39-45.SUN Yu-jiao,HOU Shu-ting,YU Zhe-zhe,et al.Study on antioxidant activity of Lycium barbarum polysaccharides[J].Journal of Shaanxi University of Science & Technology,2018,36(5):39-45.
[22] 卢旭.莲子低聚糖对双歧杆菌增殖效应的研究[D].福州:福建农林大学,2012:44-52.LU Qu.Study on the preparation and regulatory mechanisms of lotus seed oligosaccharides to probiotics and pathogens in the intestinal tract[D].Fuzhou:Fujian agriculture and Forestry University,2012:44-52.
[23] 陈林林,吴春,李伟.菟丝子黄酮的抗氧化性能研究[J].食品工业科技,2008,29(11):116-121.CHEN Lin-lin,WU Chun,LI Wei.Study on antioxidative activity of flavonoids from semen cuscutae[J].Science and Technology of Food Industry,2008,29(11):116-121.
[24] ZHANG W,ZHANG J,DING D,ZHANG L,et al.Synthes is and antioxidant properties of Lycium barbarum polysaccharides cappedselenium1nanoparticles usingteaextract[J].Artificial Cells Nanomedicine & Biotechnology,2017,7:1-8.
[25] WANNES W A,MHAMDI B,SRITI J,et al.Antioxidant activities of the essential oils and methanol extracts from myrtle(Myrtus communis var.italica L)leaf,stem and flower[J].Food & Chemical Toxicology,2010,48(5):1 362-1 370.
[26] PENG Q,SONG J J,LU X P,et al.Structure characterization of an arabinogalactan-protein fron the fruits of Lycium ruthenicum[J].Journal of Agricultural and Food Chemistry,2012,60(37):9 424-9 429.

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