Abstract
Objective: This study focuses on improving the stability and water solubility of astaxanthin. Methods: Phytosterol α-linolenic acid ester was synthesized by chemical method with phytosterol andα-linolenic acid as raw materials. Liposomes co-encapsulating astaxanthin and phytosterol α-linolenic acid ester were prepared by employing a thin-film ultrasound technique with the utilization of soybean phospholipid. Results: Based on the structure analysis by infrared spectroscopy and nuclear magnetic resonance, it has been demonstrated that the product was phytosterolα-linolenic acid ester. The purity of phytosterolα-linolenic acid ester was (90.72±2.09)% by gas chromatography. The encapsulation efficiency of liposomes co-encapsulating astaxanthin and phytosterolα-linolenic acid ester were (95.00±0.66)%,the average particle size was (158.70±9.70)nm, the polydispersity index (PDI) was 0.35±0.02, and the average zeta potential was (-33.87±2.48) mV. Transmission electron microscopy revealed that the complex liposomes were spherical with regular shape and uniform particle size distribution. Conclusion: Phytosterol α-linolenic acid ester could be applied in the preparation of astaxanthin-loaded liposomes.
Publication Date
12-28-2022
First Page
133
Last Page
138,144
DOI
10.13652/j.spjx.1003.5788.2022.80305
Recommended Citation
Yan-jun, LIU; Li, PAN; Zhen-gang, CHANG; Hao-jie, MENG; and Guo-zhi, ZHANG
(2022)
"Preparation of phytosterol α-linolenic acid ester and its application in astaxanthin-loaded liposomes,"
Food and Machinery: Vol. 38:
Iss.
12, Article 22.
DOI: 10.13652/j.spjx.1003.5788.2022.80305
Available at:
https://www.ifoodmm.cn/journal/vol38/iss12/22
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