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Abstract

Using American ginseng extract as the raw materials,formulation and preparation process of American ginseng extract rapidly dissolving tablets were studied through the single factor experiment and orthogonal experiment which evaluated by disintegration time, taste. And research results showed the optimized formulation were as follows: 20% American ginseng extract powder, 12% CMS-Na, 20% MCC, 8% L-HPC, 0.4% menthol, 1.0% sucralose, 0.2% citric acid. mannite as diluent. The orally disintegrating tablets could be obtained, with good taste, take convenience.

Publication Date

12-28-2015

First Page

212

Last Page

214

DOI

10.13652/j.issn.1003-5788.2015.06.050

References

[1] 国家药典委员会. 中华人民共和国药典一部[S]. 2010年版. 北京: 中国医药科技出版社, 2010: 122~123.
[2] 王丽君. 西洋参皂苷和多糖的活性研究[D]. 北京: 中国农业科学院, 2013.
[3] 翟鹏贵, 赵珺彦, 祝铃栋, 等. 西洋参制剂抗疲劳作用的实验研究[J]. 浙江中医药大学学报, 2007, 31(6): 761~762.
[4] Wang Chong-zhi, Aung H H, Zhang Bin, et a1. Chemopreventive effects of heat-processed Panax quinquefolius root on human breast cancer cells[J]. Anticancer Res, 2008, 28(5A): 2 545~2 551.
[5] 喻春皓, 王冲之, 袁钧苏. 西洋参抗癌研究进展—以结直肠癌为研究范例[J]. 药学学报, 2013, 48(7): 986~992.
[6] 马晓北. 西洋参[M]. 第2版. 天津: 天津科学技术出版社, 2009: 33~38.
[7] Lemmon H R, Sham J, Chau L A, et a1. High molecular weight polysaccharides are key immunomodulators in North American ginseng extracts: Characterization of the ginseng genetic signature in primary human immune cells[J]. Journal of Ethnopharmacology, 2012, 142: 1~13.
[8] 国家食品药品监督管理总局信息中心. 保健食品:西洋参\.[2015—01—24].http://app2.sfda.gov.cn/datasearchp/gzcxSearch.do?formRender=cx&page=1, 2014-12-25.
[9] 国家药品监督管理局. WS-10520(ZD-0520)-2002 西洋参颗粒标准(试行)[S]. 北京: 国家药品监督管理局, 2002.
[10] 崔福德. 药剂学[M]. 第7版. 北京: 人民卫生出版社, 2011: 258.
[11] 陈三宝. 口腔速溶钙片的研制[J]. 食品科学, 2008, 29(9): 693~695.
[12] 王宇, 梁娜, 韩旭, 等. 小儿清热止咳分散片的填充剂与崩解剂筛选[J]. 沈阳药科大学学报, 2008, 25(4): 269~274.
[13] 郑建仙, 王伟江. 高效甜味剂和甜味抑制剂的市场现状与发展展望[J]. 食品与机械, 2006, 22(1): 2~3.

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