In order to study the optimum ultrasonic-assisted extraction technology of flavonoids in hawthorn juice under pectinase treatment, the single-factor tests and orthogonal array design were employed to optimize the extraction conditions. The effects of boiling treatment time, ultrasonic extraction time, ultrasonic extraction temperature and ultrasonic power on the content of flavonoids in hawthorn juice were researched. And the hawthorn flavoinoid extraction conditions were optimized as follows: boiling treatment time 30 min, ultrasonic extract time 50 min, ultrasonic extract temperature 50 ℃ and ultrasonic power 150 W. Under the optimized extraction conditions, the content of flavonoids was 335.32 mg/100 mL. Ultrasonic extraction process remarkably decreased the extraction time than shaking extraction.

Publication Date


First Page


Last Page





[1] 国家药典委员会. 中华人民共和国药典2010年版: 一部[S]. 北京: 中国医药科技出版社, 2010: 29.
[2] Rigelsky J M, Sweet B V. Hawthorn: pharmocology and therapeutic uses[J]. American Journal of Health-System Pharmacy, 2002, 59(5): 417-422.
[3] Edwards J E, Brown P N, Talent N, et al. A review of the chemistry of the genus Crataegus[J]. Phytochemistry, 2012, 79: 5-26.
[4] Wu Jia-qi, Peng Wei, Qin Rong-xin, et al. Crataegus pinnatifida: chemical constituents, pharmacology, and potential applications[J]. Molecules, 2014, 19(2): 1 685-1 712.
[5] 骆晓沛, 张守勤, 张格, 等. 不同提取方法对山楂总黄酮含量的影响[J]. 农机化研究, 2008(9): 145-147.
[6] 杨昱, 白靖文, 俞志刚. 超声辅助提取技术在天然产物提取中的应用[J]. 食品与机械, 2011, 27(1): 170-174.
[7] 刘成莲. 超临界流体萃取与超声技术在农产品加工中的应用[J]. 农产品加工, 2008(12): 32-33.
[8] 钟烈洲. 超声波对现榨苹果汁的品质影响[D]. 杭州: 浙江大学, 2013: 5-14.
[9] Adekunte A O, Tiwari B K, Cullen P J, et al. Effect of sonication on color, ascorbic acid and yeast inactivation in tomato juice[J]. Food Chemistry, 2010, 122(3): 500-507.
[10] Bhat R, Kamaruddin N, Liong M T, et al. Sonication improves kasturi lime (Citrus microcarpa) juice quality[J]. Ultrasonic Sonochemistry, 2011, 18(6): 1 295-1 300.
[11] 高文秀, 赵文卓, 李平平. 果胶酶酶解法辅助超声波提取山楂中总黄酮的初步工艺优化[J]. 吉林化工学院学报, 2013, 30(7): 29-32.
[12] Toma M, Vinatoru M, Paniwnyk L, et al. Investigation of the effects of ultrasound on vegetal tissues during solvent extraction[J]. Ultrasonic Sonochemistry, 2001, 8(2): 137-142.
[13] Li Hai-zhou, Pordesimo L, Weiss J. High intensity ultrasound-assisted extraction of oil from soybeans[J]. Food Research International, 2004, 37(7): 731-738.
[14] 廖维良, 赵美顺, 杨红. 超声波辅助提取技术研究进展[J]. 广东药学院学报, 2012, 28(3): 347-350.
[15] Hromádková Z, Alfdi J, Ebringerová A. Study of the classical and ultrasound-assisted extraction of the corn cobxylan[J]. Industrial Crops and Products, 1999, 9(2): 101-109.
[16] 张吉祥, 欧来良. 正交试验法优化超声提取枣核总黄酮[J]. 食品科学, 2012, 33(4): 18-21.
[17] 刘北林, 董继生, 霍红. 山楂黄酮最佳提取工艺探讨[J]. 食品科学, 2007, 28(6): 167-170.
[18] 孙协军, 李秀霞, 冯彦博, 等. 山楂黄酮超高压提取工艺研究[J]. 食品工业科技, 2015, 36(2): 291-296.



To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.