Thioglycolic acid capped CdTe quantum dots (QDs) was prepared via hydrothermal synthesis method. Based on the synchronous fluorescence enhancement of CdTe QDs in the presence of streptomycin, a synchronous fluorescence method for the determination of streptomycin residue was established. Influence factors including pH value of buffer solution, concentration of CdTe QDs and reaction time were investigated. The samples were extracted with methanol by ultrasonic processing, and were added into the solution which was composed of 1.0 mL of CdTe quantum dots (3.5×10-5 mol/L) and 1.0 mL of Tris—HCl buffer solution (pH=6.0). After standing for 10 min, the synchronous fluorescence intensity were measured at 345 nm (Δλ=230 nm). The relative synchronous fluorescence intensity showed good lined relationship to streptomycin concentration in the range of 5.0×10-7~1.0×10-5 mol/L with the correlation coefficient of 0.999 7. The detection limit was 1.0×10-8 mol/L. With the advantages of simple, rapid and high sensitivity, the proposed method can be used in the determination of streptomycin residue in tomatoes samples.

Publication Date


First Page


Last Page





[1] 巩志国, 苏敏, 员丽娟, 等. 液相色谱法测定番茄制品中链霉素和双氢链霉素的残留量[J]. 化学分析计量, 2012, 21(3): 35-38.
[2] 赵志祥, 严婉荣, 陈圆, 等. 海南生姜青枯病菌对农用链霉素的敏感性测定[J]. 西南农业学报, 2016, 29(3): 570-573.
[3] 陈怡, 刘利娟, 高杨, 等. 硫酸链霉素分子印迹传感器的研究[J]. 分析化学, 2014, 42(1): 113-117.
[4] Manyanga V, Dhulipalla R L, Hoogmartens J, et al. Improved liquid chromatographic method with pulsed electrochemical detection for the analysis of kanamycin[J]. Journal of Chromatography A, 2010, 1 217(24): 3 748-3 753.
[5] 员丽娟, 万宇平, 季新成, 等. 酶联免疫吸附法测定番茄酱中链霉素和双氢链霉素的含量[J]. 理化检验: 化学分册, 2012, 48(10): 1 143-1 145.
[6] Chen Yi-qiang, Wang Zhi-qin, Wang Zhan-hui, et al. Rapid enzyme-linked immunosorbent assay and colloidal gold immunoassay for kanamycin and tobramycin in Swine tissues[J]. Journal of Agricultural and Food Chemistry, 2008, 56(9): 2 944-2 952.
[7] 谢新民, 刘志刚. HPLC法测定链麻滴鼻液中硫酸链霉素和盐酸麻黄碱的含量[J]. 西北药学杂志, 2014, 29(1): 31-34.
[8] 黄娟, 殷耀, 徐锦忠, 等. 液相色谱—串联质谱法测定花粉中的链霉素和双氢链霉素[J]. 色谱, 2014, 32(6): 566-572.
[9] Zhu Wei-xia, Yang Ji-zhou, Liu Ya-feng, et al. Simultaneous determination of 13 aminoglycoside residues in foods of animal origin by liquid chromatography-electrospray ionization tandem mass spectrometry with two consecutive solid-phase extraction steps[J]. Journal of Chromatography A, 2008, 1 207(1/2): 29-37.
[10] 宋佩, 孟萌, Sergei A Eremin, 等. 荧光偏振免疫分析方法快速检测沙拉沙星残留[J]. 分析化学, 2012, 40(8): 1 247-1 251.
[11] 王书源, 李忠海, 付湘晋, 等. 高荧光CdTe量子点荧光探针测定Cu2+[J]. 食品与机械, 2015, 31(2): 125-129.
[12] 李萌立, 李忠海, 李节, 等. 量子点荧光探针技术在食源性致病菌检测中的应用[J]. 食品与机械, 2013, 29(5): 241-244.
[13] 毛永强, 李卓然, 王继仁, 等. 基于CdTe量子点内滤效应同步荧光猝灭法测定四环素[J]. 分析测试学报, 2015, 34(1): 96-100.
[14] Vaishnavi E, Renganathan R. CdTe quantum dot as a fluorescence probe for vitamin B12 in dosage form[J]. Spectrochimica Acta Part A, 2013, 115(11): 603-609.
[15] 元晓云, 王天伦, 关婷婷, 等. 以CdTe量子点为荧光探针测定黄瓜中链霉素的残留量[J]. 分析测试学报, 2015, 34(4): 463-467.
[16] Ge Shen-guang, Lu Juan-juan, Ge Lei, et al. Development of a novel deltamethrin sensor based on molecularly imprinted silica nanospheres embedded CdTe quantum dots[J]. Spectrochimica Acta Part A, 2011, 79(5): 1 704-1 709.
[17] 中华人民共和国国家质量监督检验检疫总局, 中国国家标准化管理委员会. GB/T 22969—2008 奶粉和牛奶中链霉素、双氢链霉素和卡那霉素残留量的测定[S]. 北京: 中国标准出版社, 2009.

Included in

Food Science Commons



To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.