Establishes growth/no growth model of Staphylococcus aureus in the factors of temperature, pH and salt concentration, by R, a software for statistical analysis. The P value was obtained by the model for model parameter values were below 0.01, so reached highly significant. When the temperature at 10 ℃ to 25 ℃, the pH at 4.5 to 5.5, the Sodium chloride salt concentration from 0.5% to 14.5%, each single factor’s effect on Staphylococcus aureus’ growth/no growth was significant, and three factors affected collaborative in other selected range of values.

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[1] 徐振波, 刘晓晨, 李琳, 等. 金黄色葡萄球菌肠毒素在食源性微生物中的研究进展[J]. 现代食品科技, 2013(9): 2 317-2 324.
[2] Notermans S, Heuvelman C J. Combined effect of water activity, pH and suboptimal temperature on growth and enterotoxin production of Staphylococcus aureus[J]. Journal of Food Science, 1983(48): 1 832-1 835.
[3] Wendlandt S, Schwarz S, Silley P. Methicillin-resistant Staphylococcus aureus: A 22 foodborne pathogen[J]. Food Science and Technology, 2013(4):117-139.
[4] 孟晓荣, 张敏, 胡新婷, 等. 壳聚糖对食品中常见菌的抑制研究[J]. 食品与机械, 2007, 23(2): 90-92.
[5] Vermeulen A, Dang T D T, Geeraerd A H, et al. Modelling the unexpected effect of acetic and lactic acid in combination with pH and aw on the growth/no growth interface of Zygosaccharomyces bailii[J]. International Journal of Food Microbiology, 2008(124): 79-90.
[6] Gysemans K P M, Bernaerts K, Vermeulen A, et al. Exploring the performance of logistic regression model types on growth/no growth data of Listeria monocytogenes[J]. Food Microbiology, 2007(114): 316-331.
[7] Chen Chen, Yang Xian-shi, Li Xue-ying. Establishment of growth/no growth model for Bacillus cereus on different temperature, pH and water activity[J]. Advanced Materials Research, 2013(p): 1 558-1 565.
[8] Couvert O, Pinon A, Bergis H, et al. Validation of a stochastic modelling approach for Listeria monocytogenes growth in refrigerated foods[J]. International Journal of Food Microbiology, 2010(144): 236-242.
[9] Theys T E, Geeraerd A H, Devlieghere F, et al. On the selection of relevant environmental factors to predict microbial dynamics in solidified media[J]. Food Microbiology, 2010(27): 220-228.
[10] Van Impe J F. Modelling the influence of the inoculation level on the growth/no growth interface of Listeria monocytogenes as a function of pH, aw and acetic acid[J]. International Journal of Food Microbiology, 2009(135): 83-89.
[11] Zhang D, McQuestin O J, Mellefont L A, et al. The influence of non-lethal temperature on the rate of inactivation of vegetative bacteria in inimical environments may be independent of bacterial species. Food Microbiology, 2010(27): 453-459.
[12] Bolton L F, Frank J F. Defining the growth/no-growth interface for Listeria monocytogenes in Mexican-style cheese based on salt, pH, and moisture content[J]. Journal of Food Protection, 1999, 62(6): 601-609.
[13] Hajmeer M, Basheer I. A probabilistic neural network approach for modeling and classification of bacterial growth/no-growth data [J]. Journal of microbiological methods, 2002, 51(2): 217-226.
[14] Polese P, Del Torre M, Spaziani M, et al. A simplified approach for modelling the bacterial growth/no growth boundary [J]. Food microbiology, 2011, 28(3): 384-391.
[15] Valero A, Pérez-Rodríguez F, Carrasco E, et al. Modelling the growth boundaries of Staphylococcus aureus: Effect of temperature, pH and water activity[J]. International Journal of Food Microbiology, 2009, 133(1/2): 186-194.
[16] Fujikawa H, Morozumi S. Modelling Staphylococcus aureus growth and enterotoxin production in milk[J]. Food Microbiology, 2006, 23(3): 260-267.
[17] Skandamis P N, Stopforth J D, Kendall P A, et al. Modeling the effect of inoculum size and acid adaptation on growth/no growth interface of Escherichia coli O157:H7[J]. International Journal of Food Microbiology, 2007, 120(3): 237-249.
[18] Borneman D L, Ingham S C, Ane C. Predicting growth/no growth of Staphylococcus aureus on vacuum-packaged ready-to-eat meats[J]. Journal of Food Protection, 2009, 72(3): 539-549.

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