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Abstract

In order to realize the accurate description of the extraction process of continuous countercurrent extraction (CCE) for Astragalus polysaccharides, a mathematical model of diffusion and backmixing was established and solved. The two-phase solute distribution in the single-flow continuous countercurrent extractor was described. The scale for describing the pilot scale was established. The diffusion back-mixing numerical model of the two-phase solute distribution in the extractor was tested by multi-effect simulation CCE of Astragalus polysaccharides. The results showed that the extraction temperature was 40~70 ℃, and the solid-liquid ratio was 1:6~1:14 (g/mL), within the single factor variation range of extraction time 40~70 min, the relative error between the model prediction distribution and the actual sample concentration is controlled ≤15%, which has certain practical value. The model can realize the achieve prediction of the concentration of the two phases in the extraction process of CCE under steady state conditions.

Publication Date

1-28-2020

First Page

42

Last Page

49

DOI

10.13652/j.issn.1003-5788.2020.01.006

References

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