•  
  •  
 

Abstract

This test evaluated the auxiliary hypoglycemic effect of cakes processed from bitter almond flour, Luo Han Guo powder, resistant starch, polydextrose and other materials on patients with type 2 diabetes. The test used a self-matching design, during the 12-week test period, and subjects were interspersed with a control breakfast and a test breakfast. The subjects were tested for fasting blood glucose, 2 hours postprandial blood glucose, glycated hemoglobin, and safety indicators. The results showed that test cakes can significantly reduce the 2 h postprandial blood glucose (P≤0.01) and glycated hemoglobin (P≤0.01) in diabetic patients. There was no significant difference in effect among different test cakes, and no adverse effects on health were observed in the test.

Publication Date

3-28-2020

First Page

19

Last Page

23,33

DOI

10.13652/j.issn.1003-5788.2020.03.004

References

[1] RíOS J L,FRANCINI F,SCHINELLA G R.Natural products for the treatment of type 2 diabetes mellitus[J].Planta Medica,2015,81(12/13):975-994.
[2] 刘东波,周佳丽,李坚,等.营养干预在糖尿病治疗中的研究进展[J].食品与机械,2019,35(6):1-11.
[3] 中华医学会糖尿病学分会.中国2型糖尿病防治指南(2013年版)[J].中华内分泌代谢杂志,2014,30(10):893-942.
[4] FRANZ M J,MACLEOD J,EVERT A,et al.Academy of Nutrition and Dietetics nutrition practice guideline for type 1 and type 2 diabetes in adults:Systematic review of evidence for medical nutrition therapy effectiveness and recommendations for integration into the nutrition care process[J].Journal of the Academy of Nutrition and Dietetics,2017,117(10):1 659-1 679.
[5] YANG Min,QIN Xiao-yi.Preparation of the cake with high fiber and low sugar and its nutritional estimation[J].Modern Food Science and Technology,2010,26(10):1 124-1 126.
[6] 贺森,李久毅,赵荣华,等.低糖南瓜荞麦蛋糕的研制[J].食品工业,2016,37(9):84-87.
[7] 李科友,史清华,朱海兰,等.苦杏仁化学成分的研究[J].西北林学院学报,2004,19(2):124-126.
[8] VIGUILIOUK E,KENDALL C W C,MEJIA S B,et al.Effect of tree nuts on glycemic control in diabetes:A systematic review and meta-analysis of randomized controlled dietary trials[J].PloS one,2014,9(7):e103376.
[9] MUSA-VELOSO K,PAULIONIS L,POON T,et al.The effects of almond consumption on fasting blood lipid levels:A systematic review and meta-analysis of randomised controlled trials[J].Journal of Nutritional Science,2016,5(34):1-15.
[10] 刘雪峰,李磊,闫文亮,等.杏仁多肽的降血糖活性研究[J].内蒙古农业大学学报:自然科学版,2010,31(2):204-208.
[11] 皇甫红芳,苏占明,李刚.燕麦的营养成分与保健功效[J].现代农业科技,2016(19):275-276.
[12] 张俐勤,戚向阳,陈维军,等.罗汉果皂苷提取物对糖尿病小鼠血糖、血脂及抗氧化作用的影响[J].中国药理学通报,2006,22(2):237-240.
[13] SUZUKI Y A,MURATA Y,INUI H,et al.Triterpene glycosides of Siraitia grosvenori inhibit rat intestinal maltase and suppress the rise in blood glucose level after a single oral administration of maltose in rats[J].Journal of Agricultural and Food Chemistry,2005,53(8):2 941-2 946.
[14] VADIVEL V,KUNYANGA C N,BIESALSKI H K.Health benefits of nut consumption with special reference to body weight control[J].Nutrition,2012,28(11/12):1 089-1 097.
[15] KRIS-ETHERTON P M,PEARSON T A,WAN Ying,et al.High-monounsaturated fatty acid diets lower both plasma cholesterol and triacylglycerol concentrations[J].The American Journal of Clinical Nutrition,1999,70(6):1 009-1 015.
[16] PANIAGUA J A,DE LA SACRISTANA A G,SÁNCHEZ E,et al.A MUFA-rich diet improves posprandial glucose,lipid and GLP-1 responses in insulin-resistant subjects[J].Journal of the American College of Nutrition,2007,26(5):434-444.
[17] YOKOYAMA J,SOMEYA Y,YOSHIHARA R,et al.Effects of high-monounsaturated fatty acid enteral formula versus high-carbohydrate enteral formula on plasma glucose concentration and insulin secretion in healthy individuals and diabetic patients[J].Journal of International Medical Research,2008,36(1):137-146.
[18] LO PIPARO E,SCHEIB H,FREI N,et al.Flavonoids for controlling starch digestion:Structural requirements for inhibiting human α-amylase[J].Journal of Medicinal Chemistry,2008,51(12):3 555-3 561.
[19] COHEN A E,JOHNSTON C S.Almond ingestion at mealtime reduces postprandial glycemia and chronic ingestion reduces hemoglobin A1c in individuals with well-controlled type 2 diabetes mellitus[J].Metabolism,2011,60(9):1 312-1 317.
[20] LI Sing-chung,LIU Yen-hua,LIU Jen-fang,et al.Almond consumption improved glycemic control and lipid profiles in patients with type 2 diabetes mellitus[J].Metabolism,2011,60(4):474-479.
[21] 张俐勤.低热量甜味剂罗汉果皂甙的分离、分析及其生物活性评价[D].武汉:华中农业大学,2004:65-66.
[22] 何伟平,朱晓韵,刘丽君,等.罗汉果低血糖指数(CI)食品及其药理研究[J].轻工科技,2011(7):1-2,5.
[23] 戚向阳,陈维军,宋云飞,等.罗汉果提取物对糖尿病小鼠的降血糖作用[J].中国公共卫生,2003,19(10):1 226-1 227.
[24] 戚向阳,陈维军,张俐勤,等.罗汉果皂甙清除自由基及抗脂质过氧化作用的研究[J].中国农业科学,2006,39(2):382-388.
[25] CHEN Wei-jun,WANG Jing,QI Xiang-yang,et al.The antioxidant activities of natural sweeteners,mogrosides,from fruits of Siraitia grosvenori[J].International Journal of Food Sciences and Nutrition,2007,58(7):548-556.
[26] GULATI S,MISRA A,PANDEY R M.Effect of almond supplementation on glycemia and cardiovascular risk factors in asian indians in north india with type 2 diabetes mellitus:A 24-week study[J].Metabolic Syndrome and Related Disorders,2017,15(2):98-105.
[27] 周英,郑艳,JEFF E,等.罗汉果提取物和罗汉果苷Ⅴ对胰岛素分泌的调节作用[J].药学学报,2009,44(11):1 252-1 257.

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.