Abstract
Objective: This study aimed to establish a rapid screening method for 57 drugs illegally added to medicinal and edible food. Methods: Extracted samples were purified by QuEhERS pretreatment technology, and 57 kinds of illegal addition of drugs were separated by Waters BEH C18 column. Acetonitrile-water was used as a mobile phase for gradient elution. Mass spectrometry electrospray and multiple reaction monitoring (MRM) were used for detection and analysis. Results: The established method had good linearity, and the correlation coefficients (R2) of 57 kinds of illegal addition of drugs were all greater than 0.99. The limits of detection were 0.03~0.10 μg/kg. The average recoveries were 79.4%~92.6%, and the relative standard deviations (RSDs) were 0.86%~5.61%. Conclusion: The method is stable and sensitive and suitable for rapid qualitative and quantitative screening of 57 kinds of illegally added drugs in medicinal and edible food.
Publication Date
12-28-2022
First Page
37
Last Page
43,55
DOI
10.13652/j.spjx.1003.5788.2022.80981
Recommended Citation
Yan, QI; Qing-peng, XU; Cong, LI; Xing-fei, DENG; and Jin-qing, LI
(2022)
"Rapid screening of 57 illegally added drugs for uric acid lowering medicinal and edible food by modified QuEChERS technology,"
Food and Machinery: Vol. 38:
Iss.
12, Article 6.
DOI: 10.13652/j.spjx.1003.5788.2022.80981
Available at:
https://www.ifoodmm.cn/journal/vol38/iss12/6
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