Abstract
Chinese Baijiu distiller's grains represent a major by-product of the Baijiu brewing industry. The solid-state or liquid-state multi-strain fermentation process endows them with complex chemical compositions and functional properties, conferring considerable potential for further development. This study describes the chemical composition of Chinese Baijiu distiller's grains, discusses the differences in functional components arising from the brewing processes of various Baijiu aroma types, and evaluates advanced extraction techniques targeting core components, including proteins, dietary fibers, and polyphenols. The biological activities of Chinese Baijiu distiller's grain extracts, such as antioxidant, antihypertensive, and immunoregulatory effects, as well as their underlying mechanisms of action, are summarized. Furthermore, the application prospects of these extracts as functional food ingredients are also explored.
Publication Date
6-17-2026
First Page
242
Last Page
248
DOI
10.13652/j.spjx.1003.5788.2025.80828
Recommended Citation
Yanyong, WANG and Shuanghai, GUO
(2026)
"Research progress on the extraction of functional components from Chinese Baijiu distiller's grains and their high-value applications,"
Food and Machinery: Vol. 42:
Iss.
5, Article 28.
DOI: 10.13652/j.spjx.1003.5788.2025.80828
Available at:
https://www.ifoodmm.cn/journal/vol42/iss5/28
References
[1] YU H Y,XIE B T,KHAN R,et al.The changes in macronutrients and microbial community structure during the co-composting of white wine distillers grains and potassium silicate [J].Journal of Cleaner Production,2021,319:128681.
[2] 付娜娜,王亚美,王方正,等.白酒酒糟资源化利用现状分析[J].中国酿造,2025,44(8):9-14.FU N N,WANG Y M,WANG F Z,et al.Analysis of the current situation of resource utilization of Baijiu distiller's grains [J].China Brewing,2025,44(8):9-14.
[3] 郭帅鹏,王改琴,徐瑞,等.酒糟的营养价值及其在畜禽生产中的应用 [J].饲料工业,2025,46(14):14-19.GUO S P,WANG G Q,XU R,et al.Nutrition value of distiller's grains and its application in livestock and poultry production [J].Feed Industry,2025,46(14):14-19.
[4] 罗琳,廖菲菲,辛璇,等.黄酒糟蛋白质资源的开发利用研究进展 [J].现代食品科技,2025,41(5):364-371.LUO L,LIAO F F,XIN X,et al.Research progress of the development and utilization of protein resources in yellow wine lees[J].Modern Food Science and Technology,2025,41(5):364-371.
[5] 王慧丽,沈雪梅,陈影,等.基于不同原料的干酒糟及其可溶物（DDGS）饲用价值分析 [J].安徽农学通报,2025,31(9):87-92.WANG H L,SHEN X M,CHEN Y,et al.Analysis of feeding value of distillers dried grains with solubles （DDGS）derived from different raw materials [J].Anhui Agricultural Science Bulletin,2025,31(9):87-92.
[6] HE R,YANG Y B,LI Y S,et al.Recent progress in distiller's grains:chemical compositions and biological activities [J].Molecules,2023,28(22):7 492.
[7] 陈宝,范志勇,王丽,等.白酒糟和发酵白酒糟的营养价值及其在猪生产中的应用研究进展 [J].动物营养学报,2025,37(5):2 822-2 836.CHEN B,FAN Z Y,WANG L,et al.Research progress on nutritional value of distiller's grains and fermented distiller's grains and their application in pig production [J].Chinese Journal of Animal Nutrition,2025,37(5):2 822-2 836.
[8] 王建新.酒糟高值化利用研究进展 [J].食品安全导刊,2018(33):160-161.WANG J X.Research progress on high-value utilization of distillers' grains [J].Journal of Food Safety Guide,2018 (33):160-161.
[9] LI X J,CHEN S T,YU Y,et al.Ethanol production from mixtures of distiller's dried grains with solubles (DDGS ) and corn [J].Industrial Crops and Products,2019,129:59-66.
[10] BHANJA DEY T,CHAKRABORTY S,JAIN K K,et al.Antioxidant phenolics and their microbial production by submerged and solid state fermentation process:a review [J].Trends in Food Science & Technology,2016,53:60-74.
[11] 江思瑶,宋昊,陈晨,等.白酒酒糟中有机酸的分离提取及香气成分分析 [J].食品工业科技,2019,40(17):206-211.JIANG S Y,SONG H,CHEN C,et al.Analysis of organic acids and flavoring compositions extracted from distiller's grains[J].Science and Technology of Food Industry,2019,40(17):206-211.
[12] 唐平,山其木格,王丽,等.白酒风味化学研究方法及酱香型白酒风味化学研究进展 [J].食品科学,2020,41(17):315-324.TANG P,SHAN Q M,WANG L,et al.A review of research methods in Baijiu flavor chemistry and recent progress in the flavor chemistry of Maotai-flavored Baijiu [J].Food Science,2020,41(17):315-324.
[13] 岳小淋,向双全,钱宇,等.不同等级浓香型白酒基酒挥发性风味物质差异分析 [J].中国酿造,2025,44(6):258-265.YUE X L,XIANG S Q,QIAN Y,et al.Analysis on the difference of volatile flavor components in strong-flavor Baijiu base liquor with different grades [J].China Brewing,2025,44(6):258-265.
[14] LI H H,ZHANG X,GAO X J,et al.Comparison of the aroma-active compounds and sensory characteristics of different grades of light-flavor Baijiu [J].Foods,2023,12(6):1 238.
[15] LI S P,LIANG J J,MA Y L,et al.Physicochemical properties of red millet:a novel Chinese rice wine brewing material [J].Journal of Food Processing and Preservation,2021,45(6):e15556.
[16] 陈丽花,陈少华,荣玉芝,等.具有抗氧化活性青稞酒糟蛋白酶解液对 H2O2诱导 HepG 2细胞的保护作用 [J].现代食品科技,2024,40(3):28-38.CHEN L H,CHEN S H,RONG Y Z,et al.H2O2-induced protective effects of the antioxidant protease hydrolysate of highland barley brewer's spent grains on HepG 2 cells [J].Modern Food Science and Technology,2024,40(3):28-38.
[17] SUN H L,NI B,YANG J G,et al.Nitrogenous compounds and Chinese Baijiu:a review [J].Journal of the Institute of Brewing,2022,128(1):5-14.
[18] SHAH U,DWIVEDI D,HACKETT M,et al.Physicochemical characterisation of kafirins extracted from sorghum grain and dried distillers grain with solubles related to their biomaterial functionality [J].Scientific Reports,2021,11(1):15204.
[19] CHATZIFRAGKOU A,PRABHAKUMARI P C,KOSIK O,et al.Extractability and characteristics of proteins deriving from wheat DDGS [J].Food Chemistry,2016,198:12-19.
[20] 曾育婷,胡思齐,刘红芹,等.白酒、酒醅及丢糟中生物活性肽的研究进展 [J].中国酿造,2025,44(6):1-7.ZENG Y T,HU S Q,LIU H Q,et al.Progress in bioactive peptides in Baijiu,fermented grains and distiller's grains [J].China Brewing,2025,44(6):1-7.
[21] CHEN L H,CHEN S H,RONG Y Z,et al.Identification and evaluation of antioxidant peptides from highland barley distiller's grains protein hydrolysate assisted by molecular docking [J].Food Chemistry,2024,434:137441.
[22] JIANG Y S,XING M Z,KANG Q,et al.Pulse electric field assisted process for extraction of Jiuzao glutelin extract and its physicochemical properties and biological activities investigation [J].Food Chemistry,2022,383:132304.
[23] 张世仙,从凯龙,曾启华,等.酶法提取茅台酒糟中水溶性膳食纤维的工艺研究 [J].中国酿造,2012,31(3):97-100.ZHANG S X,CONG K L,ZENG Q H,et al.Extraction technology of water-soluble dietary fiber from Moutai vinasse by enzymatic extraction [J].China Brewing,2012,31(3):97-100.
[24] 刘军,颉向红,徐昊,等.枸杞酒糟可溶性膳食纤维提取及其理化性质研究 [J].河南农业科学,2019,48(8):160-167.LIU J,XIE X H,XU H,et al.Extraction and properties of soluble dietary fiber from Chinese wolfberry distiller's grains [J].Journal of Henan Agricultural Sciences,2019,48(8):160-167.
[25] HU H G,ZHAO Q L.Optimization extraction and functional properties of soluble dietary fiber from pineapple pomace obtained by shear homogenization-assisted extraction [J].RSC Advances,2018,8(72):41 117-41 130.
[26] 常桂英,于加平.玉米酒糟中绿原酸提取工艺研究 [J].江苏农业科学,2015,43(12):298-300.CHANG G Y,YU J P.Study on the extraction process of chlorogenic acid from corn distillers' grains [J].Jiangsu Agricultural Sciences,2015,43(12):298-300.
[27] 芮文君,赵萍,邱悦,等.响应面法优化白酒糟富里酸的提取工艺 [J].中国酿造,2017,36(9):82-86.RUI W J,ZHAO P,QIU Y,et al.Optimization of extraction technology of fulvic acid in distillers grains by response surface method [J].China Brewing,2017,36(9):82-86.
[28] 曹新志,游见明,熊俐,等.郎酒酒糟中总酚的提取与检测方法的优化 [J].中国酿造,2011,30(7):137-140.CAO X Z,YOU J M,XIONG L,et al.Optimization of extraction and detection methods of total phenol from Langjiu Liquor vinasse [J].China Brewing,2011,30(7):137-140.
[29] IFTIKHAR M,ZHANG H J,IFTIKHAR A,et al.Study on optimization of ultrasonic assisted extraction of phenolic compounds from rye bran [J].LWT-Food Science and Technology,2020,134:110243.
[30] HU S,ZHU S L,LUO J,et al.Effect of extrusion on physicochemical properties and antioxidant potential of protein isolate derived from Baijiu vinasse [J].Food Chemistry,2022,384:132527.
[31] WEI D,FAN W L,XU Y.Identification of water-soluble peptides in distilled spent grain and its angiotensin converting enzyme (ACE ) inhibitory activity based on UPLC-Q-TOF-MS and proteomics analysis [J].Food Chemistry,2021,353:129521.
[32] ZHANG L M,JIANG Y S,YIN Z T,et al.Isolation and evaluation of two angiotensin-I-converting enzyme inhibitory peptides from fermented grains (Jiupei ) used in Chinese Baijiu production [J].Rsc Advances,2018,8(65):37 451-37 461.
[33] LI C,HU Q N,LIANG Y Q,et al.Physicochemical properties and application in film preparation of prolamin from distiller's grains [J].International Journal of Food Science & Technology,2022,57(8):5 206-5 215.
[34] 祖未希,梁雅琪,李晨.白酒糟醇溶蛋白复合涂膜液对巨峰葡萄的保鲜效果 [J].食品研究与开发,2022,43(23):70-76.ZU W X,LIANG Y Q,LI C.Preservation effect of composite emulsion coating containing prolamin from Baijiu distiller's grains on kyoho grape [J].Food Research and Development,2022,43(23):70-76.
[35] YIN Z T,LIU M Y,WANG B W,et al.Extraction,identification,and in vitro anti-inflammatory activity of feruloylated oligosaccharides from Baijiu distillers' grains [J].Foods,2024,13(8):1 283.
[36] FANG H Y,CHEN Y K,CHEN H H,et al.Immunomodulatory effects of feruloylated oligosaccharides from rice bran [J].Food Chemistry,2012,134(2):836-840.
[37] LIU Y Z,LI X,QIN H,et al.Obtaining non-digestible polysaccharides from distillers' grains of Chinese Baijiu after extrusion with enhanced antioxidation capability [J].International Journal of Biological Macromolecules,2023,243:124799.
[38] MONTEAGUDO-MERA A,CHATZIFRAGKOU A,KOSIK O,et al.Evaluation of the prebiotic potential of arabinoxylans extracted from wheat distillers' dried grains with solubles (DDGS ) and in-process samples [J].Applied Microbiology and Biotechnology,2018,102(17):7 577-7 587.
[39] ROTH M,DÖRING C,JEKLE M,et al.Mechanisms behind distiller's grains impact on wheat dough and bread quality [J].Food and Bioprocess Technology,2016,9(2):274-284.
[40] KIM N H,PARK H J,LEE E H,et al.The inflammatory activity of purified-ferulic acid from Tetragonia tetragonioides[J].Journal of Applied Biological Chemistry,2019,62(3):239-246.
[41] DASAGRANDHI C,PARK S,JUNG W K,et al.Antibacterial and biofilm modulating potential of ferulic acid-grafted chitosan against human pathogenic bacteria [J].International Journal of Molecular Sciences,2018,19(8):2 157.
[42] CUI K L,ZHANG L C,LA X Q,et al.Ferulic acid and P-Coumaric acid synergistically attenuate non-alcoholic fatty liver disease through HDAC 1/PPARG-mediated free fatty acid uptake [J].International Journal of Molecular Sciences,2022,23(23):15297.
[43] SANAM M,DETHA A,ROHI N.Detection of antibacterial activity of lactic acid bacteria,isolated from Sumba mare's milk,against Bacillus cereus,Staphylococcus aureus,and Escherichia coli [J].Journal of Advanced Veterinary and Animal Research,2022,9(1):53.
[44] FRESTEDT J L.Foods,food additives,and generally regarded as safe (GRAS ) food assessments [J].Food Control and Biosecurity,2018,16:543-565.
