After the dextran oxidized and activated by NaIO4, two aldehyde groups were obtained by ring-opening reaction. Then, the addition reaction happened between activated dextran and SOD. The modified SOD could keep its enzyme activity effectively, and the stability of the modified SOD in acid, alkali, ethanol, and at high temperature was improved, respectively. It approved that the SOD was modified by dextran successfully through the Infrared spectrum analysis of its structure.

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[1] 毛绍春,李竹英,李聪. 酸果蔓中SOD酶的提取及活性测定[J]. 食品与机械,2007,23(1): 62~63,68.
[2] 杨清媛,张相年,赵树进. 聚乙二醇化学修饰超氧化物歧化酶的研究进展[J]. 中国老年学杂志,2012(20): 4 597~4 599.
[3] 齐敬总,王凤山,张鸿伟,等. 低分子肝素修饰超氧化物歧化酶及修饰酶的理化性质研究[J].中国药学杂志,2006, 41(2): 150~153.
[4] 杨学山,王本启,王正娟,等. 月桂酰氯修饰羊血超氧化物歧化酶工艺优化及酶学性质[J]. 食品科学,2014(7): 128~131.
[5] Mülbaier M, Giannis A. The synthesis and oxidative properties of polymer-supported IBX[J]. Angew. Chem. Int. Ed., 2001, 40(23): 4 393~4 394.
[6] 阎家麒,徐龙伟,高应,等. 修饰超氧化物歧化酶的制备、性质及其在化妆品中应用的研究[J].日用化学工业,1992(6): 4~9.
[7] 周志刚. 超氧化物歧化酶的化学修饰进展[J]. 安徽医药,2010(6): 623~626.
[8] Nakamura S, Kato A, Kobayashi K. New antimicrobial characteristics of lysozyme-dextran conjugate[J]. Journal of Agricultural and Food Chemistry, 1991, 39(4): 647~650.
[9] Mateo C, Palomo J M, van Langen L M, et al. A new, mild cross-linking methodology to prepare cross-linked enzyme aggregates[J]. Biotechnology and Bioengineering, 2004, 86(3): 273~276.
[10] 曹向宇,刘剑利,朱俊丰,等. 右旋糖苷修饰玉米SOD研究[J]. 食品研究与开发,2010(3): 17~19.
[11] 王会文,刘建荣,静天玉,等. 微量超氧化物歧化酶邻苯三酚/Vc测活法[J].河北大学学报(自然科学),2000, 20(1): 61~62.
[12] 舒薇, 贺丽苹, 崔堂兵, 等. 聚乙二醇修饰对木瓜凝乳蛋白酶酶学及药物生物学性质的影响[J]. 华南农业大学学报, 2006, 27(1): 65~68.
[13] 张建萍,刘恩岐,巫永华,等. 右旋糖苷对生姜蛋白酶的化学修饰及其酶学性质影响[J]. 食品科学,2013,34(9): 228~233.
[14] 赵洁,徐斐,曹慧,等. 水溶性有机溶剂对鸡肝酯酶酶活力的影响[J]. 食品科学,2012,33(15): 216~219.
[15] 蔡为荣,顾小红,汤坚. 仙人掌多糖的提取及其结构初步研究[J].食品与机械,2007,23(4): 68~71,101.
[16] 冯文娟,徐泽平,周传兵,等. 酵母β-1,3-D-葡聚糖提取及结构鉴定[J]. 食品与机械,2013,29(5): 151~153.



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